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  • Conference paper
    Foin N, Torii R, Mortier P, De Beule M, Xu Y, Davies J, Di Mario Cet al., 2012,

    , 61st Annual Scientific Session and Expo of the American-College-of-Cardiology (ACC), Publisher: ELSEVIER SCIENCE INC, Pages: E87-E87, ISSN: 0735-1097
  • Conference paper
    Prapa S, Mccarthy KP, Kilner PJ, Xu XY, Johnson MR, Ho SY, Gatzoulis MAet al., 2012,

    Biomechanical perspectives of thoracic aortic aneurysm formation in patients with a bicuspid aortic valve: an integrated analysis

    , 2nd Congress of the European-Society-of-Cardiology Council on Basic Cardiovascular Science - Frontiers in Cardiovascular Biology, Publisher: OXFORD UNIV PRESS, Pages: S86-S86, ISSN: 0008-6363
  • Journal article
    Ma CYJ, Panoskaltsis N, Kumar R, Xu XY, Mantalaris Aet al., 2012,

    , BIOCHEMICAL ENGINEERING JOURNAL, Vol: 61, Pages: 66-77, ISSN: 1369-703X
  • Journal article
    Liu D, Wood NB, Witt N, Hughes AD, Thom SA, Xu XYet al., 2012,

    , JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME, Vol: 134, ISSN: 0148-0731
  • Journal article
    Foin N, Toni R, Mortier P, De Beule M, Viceconte N, Chan PH, Davies JE, Xu XY, Krams R, Di Mario Cet al., 2012,

    , JACC-CARDIOVASCULAR INTERVENTIONS, Vol: 5, Pages: 47-56, ISSN: 1936-8798
    • Cite
    • Citations: 92
  • Journal article
    Wang Y, Pierce I, Gatehouse P, Wood N, Firmin D, Xu XYet al., 2012,

    , MEDICAL ENGINEERING & PHYSICS, Vol: 34, Pages: 17-27, ISSN: 1350-4533
    • Cite
    • Citations: 13
  • Conference paper
    Liu C, Krishnan J, Xu X-Y, 2012,

    An investigation of effects of drugs on solid tunmours within a systems-based mathematical modelling framework

    , Innovative simulation methods in healthcare
  • Journal article
    Tan FPP, Xu XY, Torii R, Wood NB, Delahunty N, Mullen M, Moat N, Mohiaddin Ret al., 2012,

    Comparison of Aortic Flow Patterns Before and After Transcatheter Aortic Valve Implantation

    , Cardiovascular Engineering and Technology, Vol: 3, Pages: 123-135

    Abstract—Little is known of the likely changes in blood flowvelocity profiles and aortic wall shear stress (WSS) followingtranscatheter aortic valve implantation (TAVI). The objectiveof this study was to investigate the effects of TAVI onflow patterns in the thoracic aorta by using cardiovascularmagnetic resonance imaging (CMR) and computational fluiddynamics (CFD). An elderly patient with aortic stenosis wasexamined using MRI pre- and post-TAVI, and CFDsimulations were carried out incorporating MRI-derivedpatient-specific anatomy and upstream flow conditions. Pre-TAVI velocity profiles demonstrated the highly disturbedturbulent flow and jet impacting the wall of the arch owing tothe partial opening of the stenosed aortic valve, with likelypathological effects. In the Post-TAVI aorta, velocity profileswere similar to those of healthy aortas with spatially moreuniform WSS and lower turbulence levels, demonstrating thefavourable effects of the TAVI procedure in restoring normalaortic flow. This study has shown both the effectiveness ofTAVI on an individual patient and the advantage of thecombined CMR and CFD method for a comprehensivepatient-specific assessment of pre- and post-TAVI aortic flowpatterns and WSS over CMR alone.
  • Journal article
    Pierce IT, Gatehouse PD, Kalodiki E, Lattimer C, Geroulakos G, Xu XY, Firmin DNet al., 2012,

    Magnetic resonance venous velocity mapping during intermittent pneumatic compression of the calf and foot

    , Phlebology, Vol: 27, Pages: 352-359
  • Journal article
    Zhang X, Luckham PF, Hughes AD, Thom S, Xu XYet al., 2011,

    , INTERNATIONAL JOURNAL OF PHARMACEUTICS, Vol: 421, Pages: 291-292, ISSN: 0378-5173
    • Cite
    • Citations: 15
  • Journal article
    Liu C, Krishnan J, Xu XY, 2011,

    , THEORETICAL BIOLOGY AND MEDICAL MODELLING, Vol: 8
    • Cite
    • Citations: 10
  • Journal article
    Su J, Gu Z, Xu XY, 2011,

    , CHEMICAL ENGINEERING SCIENCE, Vol: 66, Pages: 6069-6088, ISSN: 0009-2509
    • Cite
    • Citations: 62
  • Conference paper
    Foin N, Torii R, Mortier P, De Beule M, Viceconte N, Davies JE, Xu XY, Krams R, Di Mario Cet al., 2011,

    Sequential Side Branch and Main Vessel Dilatation instead of Kissing Balloon after Provisional Bifurcation Stenting: Lessons from Micro-CT and Computational Simulations

    , 23rd Annual Transcatheter Cardiovascular Therapeutics (TCT) Symposium, Publisher: ELSEVIER SCIENCE INC, Pages: B82-B82, ISSN: 0735-1097
  • Journal article
    Pierce IT, Gatehouse PD, Xu XY, Firmin DNet al., 2011,

    , JOURNAL OF MAGNETIC RESONANCE IMAGING, Vol: 34, Pages: 634-644, ISSN: 1053-1807
  • Journal article
    Liu C, Krishnan J, Stebbing J, Xu XYet al., 2011,

    , PHARMACOGENOMICS, Vol: 12, Pages: 1337-1348, ISSN: 1462-2416
    • Cite
    • Citations: 14
  • Journal article
    Tan FPP, Wood NB, Tabor G, Xu XYet al., 2011,

    , JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME, Vol: 133, ISSN: 0148-0731
    • Cite
    • Citations: 40
  • Conference paper
    Malkawi AH, Hinchliffe RJ, Xu XY, Pirianov G, Tornsey E, Loftus IM, Cockerill G, Thompson MMet al., 2011,

    Lamin A/C over- expression at regions exposed to high wall stress; A novel, mechano-sensitive pathway in abdominal aortic aneurysm (AAA) pathogenesis

    , Annual Meeting of the Society-of-Academic-and-Research-Surgery, Publisher: WILEY-BLACKWELL, Pages: 35-36, ISSN: 0007-1323
  • Journal article
    Starmans-Kool MJ, Stanton AV, Xu YY, Thom SAM, Parker KH, Hughes ADet al., 2011,

    , JOURNAL OF APPLIED PHYSIOLOGY, Vol: 110, Pages: 468-471, ISSN: 8750-7587
    • Cite
    • Citations: 25
  • Journal article
    Ariff BB, Glor FP, Crowe L, Xu XY, Vennart W, Firmin DN, Thom SM, Hughes ADet al., 2010,

    , RADIOLOGY, Vol: 257, Pages: 662-669, ISSN: 0033-8419
  • Conference paper
    Malkawi AH, Hinchliffe RJ, Xu XY, Pirianov G, Torsney E, Loftus IM, Cockerill GW, Thompson MMet al., 2010,

    Lamin A/C Overexpression at Regions Exposed to High Wall Stress: A Novel, Mechanosensitive Pathway in Abdominal Aortic Aneurysm (AAA) Pathogenesis

    , Scientific Sessions on Arteriosclerosis, Thrombosis and Vascular Biology, Publisher: LIPPINCOTT WILLIAMS & WILKINS, Pages: E233-E233, ISSN: 1079-5642

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