BibTex format
@article{Odufuwa:2026:10.1186/s12889-026-28554-z,
author = {Odufuwa, OG and Sheppard, RJ and Ngonyani, S and Mpelepele, AB and Kobe, D and Njohole, A and Moore, J and Lusoli, JL and Muganga, JB and Bosselmann, R and Skovmand, O and Mboma, ZM and Mbuba, E and Philipo, R and Stevenson, JC and Sherrard-Smith, E and Bradley, J and Moore, SJ},
doi = {10.1186/s12889-026-28554-z},
journal = {BMC Public Health},
title = {House modifications using insecticide-treated screening of eave and window as a vector control tool: evidence from a semi-field system in Tanzania and simulated epidemiological impact.},
url = {http://dx.doi.org/10.1186/s12889-026-28554-z},
year = {2026}
}
RIS format (EndNote, RefMan)
TY - JOUR
AB - BACKGROUND: Gaps in unimproved house structures, especially in eaves and windows, allow mosquito entry, increasing indoor vector-borne disease transmission. Simple modifications to such houses may reduce human exposure, and insecticide treatment may kill mosquitoes, benefiting all community members. This study evaluated insecticide-treated screening (ITS) for eaves and windows, incorporated with deltamethrin and piperonyl butoxide (PBO), compared to a permethrin and PBO-treated bednet in Tanzania. METHOD: A randomised Latin-square design (4 × 4) was used in four experimental huts within a large netting cage to allow mosquito recapture inside and outside of huts. Four treatments were evaluated: (1) new (12-month stored) ITS; (2) 12-month naturally-aged ITS; (3) 12-month field-used pyrethroid-PBO bednet (standard of care in Tanzania), and (4) no treatment. The study was performed for 32 nights using 30 mosquitoes per strain, per hut per night. Four laboratory-reared strains were used: malaria vectors (Anopheles arabiensis and An. funestus), dengue vector (Aedes aegypti), and nuisance biting (Culex quinquefasciatus). Recaptured mosquitoes were assessed for mortality at 72 h, blood-feeding, and hut entry. A simulation with a modified mechanistic model tracking Plasmodium falciparum malaria was used to illustrate potential epidemiological impact from these products. RESULTS: Against all mosquito species compared to 12-month aged pyrethroid-PBO-treated bednet, new ITS induced higher mortality [Odds Ratio:2.25(95%Confidence Interval:1.65-3.06),p < 0.0001], and aged-ITS was similar [OR:0.80(95%CI:0.59-1.08),p = 0.141]. Both new and aged ITS significantly (p < 0.0001) reduced mosquito blood-feeding [new OR:0.02(95% CI:0.01-0.03); aged OR:0.09(95%CI:0.05-0.14)] and hut entry [new IRR:0.10(95%CI:0.08-0.13); aged IRR:0.25(95%CI:0.21-0.31)]. Transmission model estimates indicate epidemiological impacts of I
AU - Odufuwa,OG
AU - Sheppard,RJ
AU - Ngonyani,S
AU - Mpelepele,AB
AU - Kobe,D
AU - Njohole,A
AU - Moore,J
AU - Lusoli,JL
AU - Muganga,JB
AU - Bosselmann,R
AU - Skovmand,O
AU - Mboma,ZM
AU - Mbuba,E
AU - Philipo,R
AU - Stevenson,JC
AU - Sherrard-Smith,E
AU - Bradley,J
AU - Moore,SJ
DO - 10.1186/s12889-026-28554-z
PY - 2026///
TI - House modifications using insecticide-treated screening of eave and window as a vector control tool: evidence from a semi-field system in Tanzania and simulated epidemiological impact.
T2 - BMC Public Health
UR - http://dx.doi.org/10.1186/s12889-026-28554-z
UR - https://www.ncbi.nlm.nih.gov/pubmed/42464169
ER -