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  • Journal article
    McGregor AH, Probyn K, Cro S, Dore CJ, Burton AK, Balague F, Pincus T, Fairbank Jet al., 2014,

    , SPINE, Vol: 39, Pages: 1044-1054, ISSN: 0362-2436
    • Cite
    • Citations: 33
  • Journal article
    Akhtar KSN, Chen A, Standfield NJ, Gupte CMet al., 2014,

    , Curr Rev Musculoskelet Med, Vol: 7, Pages: 155-160, ISSN: 1935-973X

    Surgical training has followed the master-apprentice model for centuries but is currently undergoing a paradigm shift. The traditional model is inefficient with no guarantee of case mix, quality, or quantity. There is a growing focus on competency-based medical education in response to restrictions on doctors' working hours and the traditional mantra of "see one, do one, teach one" is being increasingly questioned. The medical profession is subject to more scrutiny than ever before and is facing mounting financial, clinical, and political pressures. Simulation may be a means of addressing these challenges. It provides a way for trainees to practice technical tasks in a protected environment without putting patients at risk and helps to shorten the learning curve. The evidence for simulation-based training in orthopedic surgery using synthetic models, cadavers, and virtual reality simulators is constantly developing, though further work is needed to ensure the transfer of skills to the operating theatre.
  • Book chapter
    Fletcher A, Pearson J, Molleson T, Abel R, Ambers J, Wiles CCet al., 2014,

    Beneath the surface: imaging techniques and the Jericho Skull

    , Regarding the Dead Human Remains in the British Museum, Editors: Fletcher, Antoine, Hill, Publisher: British Museum Publications Limited, ISBN: 9780861591978

    A key publication on the British Museum's approach to the ethical issues surrounding the inclusion of human remains in museum collections and possible solutions to the dilemmas relating to their curation, storage, access management and ...
  • Book chapter
    Fletcher A, Pearson J, Molleson T, Abel R, Ambers J, Wiles CCRet al., 2014,

    Beneath the surface: imaging techniques and the Jericho Skull

    , Regarding the Dead Human Remains in the British Museum, Publisher: British Museum Publications Limited, ISBN: 9780861591978

    A key publication on the British Museum's approach to the ethical issues surrounding the inclusion of human remains in museum collections and possible solutions to the dilemmas relating to their curation, storage, access management and ...
  • Conference paper
    Langley RE, Trinh D, Jovic G, Cafferty F, Honeyfield L, Abel R, Stone M, Kynaston H, Alhasso AA, Scrase CD, Paez EM, Spittle B, Bara A, Parmar MMK, Abel PDet al., 2014,

    , 50th Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), Publisher: LIPPINCOTT WILLIAMS & WILKINS, ISSN: 0732-183X
  • Journal article
    Atallah L, Wiik A, Lo B, Cobb JP, Amis AA, Yang G-Zet al., 2014,

    , PHYSIOLOGICAL MEASUREMENT, Vol: 35, Pages: N29-N40, ISSN: 0967-3334
    • Cite
    • Citations: 18
  • Conference paper
    Campbell IC, Coudrillier B, Abel RL, Ethier CRet al., 2014,

    Effects of Lamina Cribrosa Microarchitecture on Biomechanics in Glaucoma

    , Publisher: ASSOC RESEARCH VISION OPHTHALMOLOGY INC, ISSN: 0146-0404
  • Conference paper
    Coudrillier B, Abel RL, Albon J, Campbell IC, Ethier CRet al., 2014,

    Micro-computed Tomography (μCT) for the Structural Analysis of the Lamina Cribrosa (LC)

    , Publisher: ASSOC RESEARCH VISION OPHTHALMOLOGY INC, ISSN: 0146-0404
  • Conference paper
    Ethier CR, Campbell IC, Coudrillier B, Abel RLet al., 2014,

    Automated detection of Lamina Cribrosa (LC) beam microarchitecture from imaging data using a Frangi filter

    , Publisher: ASSOC RESEARCH VISION OPHTHALMOLOGY INC, ISSN: 0146-0404
  • Journal article
    Duffell LD, Southgate DFL, Gulati V, McGregor AHet al., 2014,

    , GAIT & POSTURE, Vol: 39, Pages: 1057-1061, ISSN: 0966-6362
    • Cite
    • Citations: 74
  • Journal article
    Gupte CM, Schaerf DA, Sandison A, Bull AMJ, Amis AAet al., 2014,

    , ISRN Anatomy, Vol: 2014, ISSN: 2314-4726

    Aim. To investigate the existence of neural structures within the meniscofemoral ligaments (MFLs) of the human knee. Methods. The MFLs from 8 human cadaveric knees were harvested. 5 μm sections were H&E-stained and examined under light microscopy. The harvested ligaments were then stained using an S100 monoclonal antibody utilising the ABC technique to detect neural components. Further examination was performed on 60–80 nm sections under electron microscopy. Results. Of the 8 knees, 6 were suitable for examination. From these both MFLs existed in 3, only anterior MFLs were present in 2, and an isolated posterior MFL existed in 1. Out of the 9 MFLs, 4 demonstrated neural structures on light and electron microscopy and this was confirmed with S100 staining. The ultrastructure of these neural components was morphologically similar to mechanoreceptors. Conclusion. Neural structures are present in MFLs near to their meniscal attachments. It is likely that the meniscofemoral ligaments contribute not only as passive secondary restraints to posterior draw but more importantly to proprioception and may therefore play an active role in providing a neurosensory feedback loop. This may be particularly important when the primary restraint has reduced function as in the posterior cruciate ligament—deficient human knee.
  • Journal article
    Newman SD, Lotfibakhshaiesh N, O'Donnell M, Walboomers XF, Horwood N, Jansen JA, Amis AA, Cobb JP, Stevens MMet al., 2014,

    , TISSUE ENGINEERING PART A, Vol: 20, Pages: 1850-1857, ISSN: 1937-3341

    The use of endosseous implants is firmly established in skeletal reconstructive surgery, with rapid and permanent fixation of prostheses being a highly desirable feature. Implant coatings composed of hydroxyapatite (HA) have become the standard and have been used with some success in prolonging the time to revision surgery, but aseptic loosening remains a significant issue. The development of a new generation of more biologically active coatings is a promising approach for tackling this problem. Bioactive glasses are an ideal candidate material due to the osteostimulative properties of their dissolution products. However, to date, they have not been formulated with stability to devitrification or thermal expansion coefficients (TECs) that are suitable for stable coating onto metal implants while still retaining their bioactive properties. Here, we present a strontium-substituted bioactive glass (SrBG) implant coating which has been designed to encourage peri-implant bone formation and with a TEC similar to that of HA. The coating can be successfully applied to roughened Ti6Al4V and after implantation into the distal femur and proximal tibia of twenty-seven New Zealand White rabbits for 6, 12, or 24 weeks, it produced no adverse tissue reaction. The glass dissolved over a 6 week period, stimulating enhanced peri-implant bone formation compared with matched HA coated implants in the contralateral limb. Furthermore, superior mechanical fixation was evident in the SrBG group after 24 weeks of implantation. We propose that this coating has the potential to enhance implant fixation in a variety of orthopedic reconstructive surgery applications.
  • Journal article
    Cobb JP, 2014,

    , BMJ-BRITISH MEDICAL JOURNAL, Vol: 348, ISSN: 1756-1833
  • Journal article
    Dodds AL, Halewood C, Gupte CM, Williams A, Amis AAet al., 2014,

    , BONE & JOINT JOURNAL, Vol: 96B, Pages: 325-331, ISSN: 2049-4394
    • Cite
    • Citations: 321
  • Journal article
    Duffell LD, Hope N, McGregor AH, 2014,

    , PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART H-JOURNAL OF ENGINEERING IN MEDICINE, Vol: 228, Pages: 206-210, ISSN: 0954-4119
    • Cite
    • Citations: 73
  • Journal article
    McGregor AH, Probyn K, Cro S, Doré CJ, Burton AK, Balagué F, Pincus T, Fairbank Jet al., 2014,

    , J Evid Based Med, Vol: 7, Pages: 62-63
  • Journal article
    Buckeridge EM, Bull AMJ, Mcgregor AH, 2014,

    , SPORTS BIOMECHANICS, Vol: 13, Pages: 47-61, ISSN: 1476-3141
    • Cite
    • Citations: 25
  • Conference paper
    Spulber I, Papi E, Chen Y-M, Anastasova-Ivanova S, Bergmann J, Georgiou P, McGregor AHet al., 2014,

    Development of a wireless multi-functional body sensing platform for smart garment integration

    , IEEE Biomedical Circuits and Systems Conference (BioCAS), Publisher: IEEE, Pages: 157-160, ISSN: 2163-4025
  • Journal article
    Tay C, Khajuria A, Gupte C, 2014,

    , INTERNATIONAL JOURNAL OF SURGERY, Vol: 12, Pages: 626-633, ISSN: 1743-9191
    • Cite
    • Citations: 72
  • Journal article
    Hunt NC, Ghosh KM, Blain AP, Athwal KK, Rushton SP, Amis AA, Longstaff LM, Deehan DJet al., 2014,

    , J. Orthop. Res., Vol: 32, Pages: 1208-1213, ISSN: 1554-527X

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