51³Ô¹ÏÍø

Omicron – latest research and expert views as UK cases hit all-time high

by Deborah Evanson, Emily Head, Conrad Duncan

ARTIST IMPRESSION OF COVID-19

Experts from 51³Ô¹ÏÍø are advancing understanding of the Omicron variant and how we can protect against it as the UK’s booster rollout gathers speed.

As case numbers , here’s what 51³Ô¹ÏÍø experts had to say this week. 

Record UK case numbers 

The UK saw its highest number of daily COVID infections reported this week, when 88,376 new cases were recorded on Thursday – a figure that has been driven by a surge in Omicron infections. 

Just because you’ve had COVID before, it’s not going to protect you against Omicron. Professor Neil Ferguson School of Public Health

Professor Peter Openshaw, Professor of Experimental Medicine at 51³Ô¹ÏÍø, and Professor Neil Ferguson, Director of 51³Ô¹ÏÍø’s MRC Centre for Global Infectious Disease Analysis (MRC GIDA), both  on Wednesday night to discuss the sharp rise in cases. 

Professor Ferguson told PM that people who have previously been infected with Alpha or Delta “probably only have about 20 per cent protection against reinfection” from the new variant. 

He added: “Just because you’ve had COVID before, it’s not going to protect you [from reinfection] against Omicron.” 

Earlier this week, Professor Ferguson also  that the Omicron variant had the potential to cause up to 10,000 hospitalisations a day if it is as virulent as Delta as he warned the UK was already seeing a “very explosive wave of infection”. 

However, Professor Wendy Barclay, Head of the Department of Infectious Disease at 51³Ô¹ÏÍø,  on Tuesday that it was too soon to know the severity of disease caused by the variant. 

The UK saw its highest number of daily COVID infections reported this week
The UK saw its highest number of daily COVID infections reported this week

Ambitious booster targets 

This week the Government announced it would accelerate its booster programme, aiming to offer booster jabs to everyone over 18 before the end of the year. 

The Government pledged to deliver up to a million jabs a day in order to deliver the ambitious target. 

Many in the healthcare sector are doubtful that the country will be able to reach the target set by the Government. Speaking (starts at 19.30 mins) on Monday 13 December, Professor Azeem Majeed, Professor of Primary Care and Public Health at 51³Ô¹ÏÍø, said it’s good to mobilise people and the NHS, but at the same time the target should be realistic.   

Professor Azeem Majeed
Professor Azeem Majeed

He said: “We will increase the pace of the programme but I can’t see us reaching a million vaccines a day for some time. At the moment, we’re doing around 400,000 vaccines a day on average, so a million a day implies a nearly three-fold increase from our current rate. Given that this plan was announced yesterday evening, this is probably too radical a target.” 

Professor Majeed also about the Omicron variant and offered reassurance about the safety of COVID vaccines as he encouraged people to get their boosters in an interview with the Daily Mirror. 

He said: “Research has shown that Covid-19 vaccines, including boosters, are very safe with only a very small risk of serious side-effects. The risks from a COVID-19 infection are far higher than from vaccination.” 

More support for boosters 

The Omicron variant is hampering the effectiveness of current vaccines, it was reported this week, with two doses offering almost no protection against infection although they should still greatly reduce the risk of needing hospital care. 

Various studies have shown that the antibodies a person has after two doses of a COVID vaccine were much less effective against Omicron. 

Professor Danny Altmann, Professor of Immunology at 51³Ô¹ÏÍø, " 

But booster jabs improve both the quality and quantity of antibodies, offering more protection. 

Professor Charles Bangham, from the Institute of Infection at 51³Ô¹ÏÍø, : "The purpose of the booster is to increase the strength of the antibody and T-cell immunity, so that if you are reinfected, it becomes a trivial infection: you are less unwell, and you are less likely to transmit it to others."

Pop-up vaccinations at 51³Ô¹ÏÍø

Cut waiting time to speed up roll-out 

at walk-in centres, as adults across the UK scrambled to get a booster jab. 

Health Secretary Sajid Javid this week said that he was reviewing the waiting time for observation after COVID-19 vaccination, in order to speed up booster efforts. 

Professor Azeem Majeed wrote: "If the Government wants to increase the number of Covid-19 vaccinations, then the MHRA needs to urgently review the 15-minute waiting period after vaccination. 

"This substantially reduces the efficiency and throughput of vaccine clinics, as well as vaccinations for the housebound." 

Article text (excluding photos or graphics) © 51³Ô¹ÏÍø.

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Reporter

Deborah Evanson

Communications Division

Emily Head

Communications Division

Conrad Duncan

Communications Division