51³Ô¹ÏÍø

Could mink farms be the source of the next flu pandemic?

by Ryan O'Hare

Mink in a European fur farm

Urgent action is needed to address the significant risk posed by fur farms for the emergence of future viral pandemics, 51³Ô¹ÏÍø scientists warn.

Mink fur farms could provide the optimum conditions for H5N1 influenza to mutate and make the jump to humans, potentially leading to the next global pandemic, warn scientists from 51³Ô¹ÏÍø.  

In an published this week, leading virologists from 51³Ô¹ÏÍø highlight mink fur farming as a major global biosecurity risk, calling for urgent action to address the danger of a looming global pandemic.

Fur farming should be in the same category of high-risk practices as the bushmeat trade and live animal markets. These activities all increase the likelihood of future pandemics. Professor Wendy Barclay and Dr Thomas Peacock Department of Infectious Disease

The call coincides with reports this month of .

Writing in the scientific journal, PNAS, Professor Wendy Barclay, head of the Department of Infectious Disease at 51³Ô¹ÏÍø, and , a virologist from 51³Ô¹ÏÍø and The Pirbright Virology Institute, highlight the significant risk from fur farms, adding that the practice should be placed in the same category as high-risk practices such as bushmeat trade and live animal markets.

Among the concerns, they highlight:

  • Mink fur farms pose the most significant, avoidable biological threat for the next global influenza pandemic. The animals can and other respiratory viruses, and there is evidence of viruses jumping from the animals to other species (including SARS-CoV-2 and H5N1).
  • The researchers argue that fur farming poses a greater threat to global health than poultry or pig farming, due to a combination of the mink's biology, housing conditions, and a lack of regulation and protective equipment in the handling and culling of animals.
  • Ongoing H5N1 influenza outbreaks pose a significant pandemic risk, but so far cases have largely been restricted to wild birds or solitary mammals with little human interaction. Mink farms provide the perfect opportunity for H5N1 to spread quickly between animals and for viral mutations to accumulate, including adaptations which make it more transmissible to and between humans.
  • The researchers warn that the use of antivirals in mink farms is not a viable option due to the significant risk of viruses developing resistance (termed antimicrobial resistance), rendering the drugs ineffective for treating humans.
  • They argue that restricting and/or heavily regulating mink fur farming in Europe and North America offers the single most effective, readily enforceable strategy to reduce the risk of an H5N1 pandemic event in the near future.

The authors warn: ‘Fur farming should be in the same category of high-risk practices as the bushmeat trade and live animal markets. These activities all increase the likelihood of future pandemics. At the very least, biosecurity practices and active surveillance at fur farms must be reviewed, greatly enhanced, and closely enforced.’

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Read the full opinion piece ‘Mink farming poses risks for future viral pandemics’, is published in PNAS.  

Article text (excluding photos or graphics) © 51³Ô¹ÏÍø.

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Reporter

Ryan O'Hare

Communications Division